Scientists study the secret of longevity among three sisters in Brazil
The University of São Paulo is studying the genetic and environmental factors behind the longevity of three Brazilian sisters who have surpassed the age of 100.
Translated by Qiyas from القبس — Original source
Three Brazilian sisters, whose combined ages total 316 years, may help researchers unlock the secrets of longevity after Guinness World Records awarded them this month the title of the world’s oldest living triplet sisters. The “DNA Longevity” project, a study led by researcher Mayana Zatz from the University of São Paulo, aims to explore the biological factors underlying aging. Findings drawn from the case of the three sisters could help scientists explain why some individuals maintain exceptional physical and cognitive abilities at very advanced ages. Researchers will compare individuals who have surpassed 90 and 100 years of age with those who have experienced frailty, cognitive decline, or chronic diseases, in search of traits associated with longevity.
Zatz, coordinator of the university’s Human Genome Research Center, said, “Through DNA testing, we are looking for protective genes, and we know there are several of them... The more people who reach 100 years of age, especially families with multiple centenarians, the more precise our research becomes in identifying them.”
Scientists believe that genetic factors may play a larger role than environmental influences in maintaining health and functional abilities in later life. The identities of the sisters—Zulina de Deus Nunes, 103; Zoraida de Deus Mota, 104; and Levita de Deus Nunes, 109, who live in Rio de Janeiro—were verified by Longevity Quest, an international organization that validates longevity records and collaborates with Guinness World Records.
Ben Meyer, CEO of Longevity Quest, said, “When sisters reach this age, there is certainly a strong genetic component... But because they live close to each other, they also benefit from a support network, as family can assist them when needed. There is certainly a social component as well.”
The three sisters attribute their longevity to a healthy diet and an active lifestyle. Zulina recalled her childhood spent swimming and fishing in rivers, saying, “Everything was fresh. We didn’t have a refrigerator.” Zoraida added, “Breastfeeding is very important.” Levita looks back on her life without regret, reminiscing, “I had a happy childhood and adolescence. I have nothing to complain about.”
Researchers hope to understand how genetic factors, rather than lifestyle alone, contribute to protecting the heart, muscles, and cognitive functions from the destructive effects of aging.
